p53: a frequent target for genetic abnormalities in lung cancer
作者： T Takahashi , M. Nau , I Chiba , M. Birrer , R. Rosenberg
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摘要: … vitro studies have suggested the possibility that p53 acts asan anti-oncogene (8-10),we explored the status of the p53 gene in lung cancer. We examined 30 lung cancer cell lines (11) (…
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John D. Minna, Adi F. Gazdar, Paul J. Marangos, Terry W. Moody, Mark H. Zweig, Gerold Bepler, Desmond N. Carney, John G. Guccion, Establishment and Identification of Small Cell Lung Cancer Cell Lines Having Classic and Variant Features Cancer Research. ,vol. 45, pp. 2913- 2923 ,(1985)
P Hinds, C Finlay, A J Levine, Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. Journal of Virology. ,vol. 63, pp. 739- 746 ,(1989) , 10.1128/JVI.63.2.739-746.1989
Bruce Ponder, Gene losses in human tumours Nature. ,vol. 335, pp. 400- 402 ,(1988) , 10.1038/335400A0
B Vogelstein, E. Fearon, S. Kern, Hamilton, A. Preisinger, Y Nakamura, R White, Allelotype of colorectal carcinomas Science. ,vol. 244, pp. 207- 211 ,(1989) , 10.1126/SCIENCE.2565047
H. Masuda, C. Miller, H. P. Koeffler, H. Battifora, M. J. Cline, Rearrangement of the p53 gene in human osteogenic sarcomas. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 7716- 7719 ,(1987) , 10.1073/PNAS.84.21.7716
J. Dunn, R. Phillips, A. Becker, B. Gallie, Identification of germline and somatic mutations affecting the retinoblastoma gene. Science. ,vol. 241, pp. 1797- 1800 ,(1988) , 10.1126/SCIENCE.3175621
J. R. Jenkins, K. Rudge, P. Chumakov, G. A. Currie, The cellular oncogene p53 can be activated by mutagenesis. Nature. ,vol. 317, pp. 816- 818 ,(1985) , 10.1038/317816A0
M. Isobe, B. S. Emanuel, D. Givol, M. Oren, C. M. Croce, Localization of gene for human p53 tumour antigen to band 17p13 Nature. ,vol. 320, pp. 84- 85 ,(1986) , 10.1038/320084A0
Andrew P. Feinberg, Bert Vogelstein, A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity Analytical Biochemistry. ,vol. 132, pp. 6- 13 ,(1983) , 10.1016/0003-2697(83)90418-9
Marion M. Nau, Burke J. Brooks, James Battey, Edward Sausville, Adi F. Gazdar, Ilan R. Kirsch, O. Wesley McBride, Virginia Bertness, Gregory F. Hollis, John D. Minna, L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature. ,vol. 318, pp. 69- 73 ,(1985) , 10.1038/318069A0