CHAPTER 21 – Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia

摘要: This chapter focuses on the follicle selection that is regulated by discriminating atresia of growing follicles and describes regulation factors affect follicular atresia. It briefs some which might regulate or development observations suggest a novel cell-death receptor decoy in regulating porcine ovaries. Apoptosis considered as mechanism underlying ovarian Specific apoptosis-related genes, such caspase-3 apoptotic protease activating factor-1, express granulosa cells atretic specific changes glycoconjugates cell surface membrane-glycoprotein, act regulators for phagocytosis neighboring granulose follicles. Expression levels kinase cascades, entry into death proliferation cells, change during Studies have reported degeneration mammalian ovaries can be explained, at least part, endocrine theca interna layer. Histological, cytological, biochemical examination degenerating cumulus confirmed apoptosis occurs but not oocytes tertiary early stage