Human Beta-Defensin-1 Suppresses Tumor Migration and Invasion and Is an Independent Predictor for Survival of Oral Squamous Cell Carcinoma Patients
作者： Qi Han , Ruinan Wang , Chongkui Sun , Xin Jin , Dongjuan Liu
DOI: 10.1371/JOURNAL.PONE.0091867
关键词:
摘要: Background Human beta-defensin-1 (hBD-1) has recently been considered as a candidate tumor suppressor in renal and prostate cancer. The aim of this study was to investigate the role hBD-1 progression oral squamous cell carcinoma (OSCC) its potential diagnostic/prognostic biomarker therapeutic target for OSCC.
core.ac.uk
harvard.edu
paperity.org参考文章(40)
Junko Nishitani, Stanley F. Nelson, Zugen Chen, Hongying Chen, Feng Liu, Xuan Liu, Min Qin, Identification of genes required for immortalization in human papillomavirus-infected human oral keratinocytes. Cellular and Molecular Biology. ,vol. 48, ,(2002)
Amanda P Struckhoff, Manish K Rana, Rebecca A Worthylake, RhoA can lead the way in tumor cell invasion and metastasis. Frontiers in Bioscience. ,vol. 16, pp. 1915- 1926 ,(2011) , 10.2741/3830
Leslie H Sobin, Carolyn C. Compton, TNM seventh edition: What's new, what's changed Cancer. ,vol. 116, pp. 5336- 5339 ,(2010) , 10.1002/CNCR.25537
Ole E. Sørensen, Dharma R. Thapa, Adam Rosenthal, Lide Liu, Alice A. Roberts, Tomas Ganz, Differential Regulation of β-Defensin Expression in Human Skin by Microbial Stimuli The Journal of Immunology. ,vol. 174, pp. 4870- 4879 ,(2005) , 10.4049/JIMMUNOL.174.8.4870
Liang Hu, Sze Hang Lau, Chi-Hung Tzang, Jian-Ming Wen, Weisheng Wang, Dan Xie, Minghui Huang, Yi Wang, Meng-Chao Wu, Jie-Fu Huang, Wei-Fen Zeng, Jonathan S T Sham, Mengsu Yang, Xin-Yuan Guan, Association of Vimentin overexpression and hepatocellular carcinoma metastasis Oncogene. ,vol. 23, pp. 298- 302 ,(2004) , 10.1038/SJ.ONC.1206483
Carlton D Donald, Carrie Q Sun, So Dug Lim, Jill Macoska, Cynthia Cohen, Mahul B Amin, Andrew N Young, Tomas A Ganz, Fray F Marshall, John A Petros, Cancer-Specific Loss of β-Defensin 1 in Renal and Prostatic Carcinomas Laboratory Investigation. ,vol. 83, pp. 501- 505 ,(2003) , 10.1097/01.LAB.0000063929.61760.F6
S. Joly, L. M. Compton, C. Pujol, Z. B. Kurago, J. M. Guthmiller, Loss of human β-defensin 1, 2, and 3 expression in oral squamous cell carcinoma Oral Microbiology and Immunology. ,vol. 24, pp. 353- 360 ,(2009) , 10.1111/J.1399-302X.2009.00512.X
Sophie Joly, Connie C. Organ, Georgia K. Johnson, Paul B. McCray, Janet M. Guthmiller, Correlation between β-defensin expression and induction profiles in gingival keratinocytes Molecular Immunology. ,vol. 42, pp. 1073- 1084 ,(2005) , 10.1016/J.MOLIMM.2004.11.001
Rebecca S. Bullard, Willietta Gibson, Sudeep K. Bose, Jamila K. Belgrave, Andre C. Eaddy, Corey J. Wright, Debra J. Hazen-Martin, Janice M. Lage, Thomas E. Keane, Tomas A. Ganz, Carlton D. Donald, Functional analysis of the host defense peptide Human Beta Defensin-1: new insight into its potential role in cancer. Molecular Immunology. ,vol. 45, pp. 839- 848 ,(2008) , 10.1016/J.MOLIMM.2006.11.026
Jing Li, Changyang Gong, Xiaodong Feng, Xikun Zhou, Xiaoping Xu, Liang Xie, Ruinan Wang, Dunfang Zhang, Hui Wang, Peng Deng, Min Zhou, Ning Ji, Yu Zhou, Yun Wang, Zhiyong Wang, Ga Liao, Ning Geng, Liangyin Chu, Zhiyong Qian, Zhi Wang, Qianming Chen, Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts. PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0033860