Efficient production of L-lactic acid by newly isolated thermophilic Bacillus coagulans WCP10-4 with high glucose tolerance.

作者: Xingding Zhou , Lidan Ye , Jin Chuan Wu

DOI: 10.1007/S00253-013-4710-7

关键词:

摘要: A thermophilic Bacillus coagulans WCP10-4 with tolerance to high concentration of glucose was isolated from soil and used produce optically pure l-lactic acid starch. In batch fermentation at pH 6.0, 240 g/L completely consumed giving 210 a yield 95 % productivity 3.5 g/L/h. simultaneous saccharification 50 °C without sterilizing the medium, 200 corn starch producing 202.0 acid. To best our knowledge, this strain shows highest osmotic among strains ever reported for lactic production. This is first report production under non-sterilized condition.

参考文章(26)
Dong-Mei Bai, Qiang Wei, Zhi-Hui Yan, Xue-Ming Zhao, Xin-Gang Li, Shi-Min Xu, Fed-batch fermentation of Lactobacillus lactis for hyper-production of L-lactic acid. Biotechnology Letters. ,vol. 25, pp. 1833- 1835 ,(2003) , 10.1023/A:1026276925649
Kursad Turksen, Isolation and characterization Humana Press. ,(2006)
Jerald J. Baronofsky, Wilhelmus J. A. Schreurs, Eva R. Kashket, Uncoupling by Acetic Acid Limits Growth of and Acetogenesis by Clostridium thermoaceticum. Applied and Environmental Microbiology. ,vol. 48, pp. 1134- 1139 ,(1984) , 10.1128/AEM.48.6.1134-1139.1984
Edward Green, Muhammad Javed, Renia Gemmell, Lactic acid production ,(2002)
Sara L. Walton, Kenneth M. Bischoff, Adriaan R. P. van Heiningen, G. Peter van Walsum, Production of lactic acid from hemicellulose extracts by Bacillus coagulans MXL-9 Journal of Industrial Microbiology & Biotechnology. ,vol. 37, pp. 823- 830 ,(2010) , 10.1007/S10295-010-0727-4
Xiang-Yang Ge, Jian Yuan, Hao Qin, Wei-Guo Zhang, Improvement of L-lactic acid production by osmotic-tolerant mutant of Lactobacillus casei at high temperature. Applied Microbiology and Biotechnology. ,vol. 89, pp. 73- 78 ,(2011) , 10.1007/S00253-010-2868-9
Kenji Okano, Tsutomu Tanaka, Chiaki Ogino, Hideki Fukuda, Akihiko Kondo, Biotechnological production of enantiomeric pure lactic acid from renewable resources: recent achievements, perspectives, and limits. Applied Microbiology and Biotechnology. ,vol. 85, pp. 413- 423 ,(2010) , 10.1007/S00253-009-2280-5
Yukihiro Tashiro, Wataru Kaneko, Yanqi Sun, Keisuke Shibata, Kentaro Inokuma, Takeshi Zendo, Kenji Sonomoto, Continuous d-lactic acid production by a novelthermotolerant Lactobacillus delbrueckii subsp. lactis QU 41 Applied Microbiology and Biotechnology. ,vol. 89, pp. 1741- 1750 ,(2011) , 10.1007/S00253-010-3011-7
Jiayang Qin, Bo Zhao, Xiuwen Wang, Limin Wang, Bo Yu, Yanhe Ma, Cuiqing Ma, Hongzhi Tang, Jibin Sun, Ping Xu, Non-Sterilized Fermentative Production of Polymer-Grade L-Lactic Acid by a Newly Isolated Thermophilic Strain Bacillus sp. 2–6 PLoS ONE. ,vol. 4, pp. e4359- ,(2009) , 10.1371/JOURNAL.PONE.0004359
Milind A. Patel, Mark S. Ou, Roberta Harbrucker, Henry C. Aldrich, Marian L. Buszko, Lonnie O. Ingram, K. T. Shanmugam, Isolation and characterization of acid-tolerant, thermophilic bacteria for effective fermentation of biomass-derived sugars to lactic acid. Applied and Environmental Microbiology. ,vol. 72, pp. 3228- 3235 ,(2006) , 10.1128/AEM.72.5.3228-3235.2006