Production of erythroid cells from human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPS)
作者： D.J. Anstee
DOI: 10.1016/J.TRACLI.2010.05.005
关键词:
摘要: Erythroid progenitors can be generated ex vivo from human embryonic stem cells (hESC) or induced pluripotent (hiPS). Development of laboratory scale culture conditions capable generating mature functional erythrocytes would open the possibility for manufacture therapeutic quantities red and thereby new clinical transfusion products. Current attempts to produce reveal need greater understanding process whereby primitive erythropoiesis switches definitive fetal adult factors driving erythrocyte maturation. Studies with have already yielded encouraging results but biconcave yet these cells.
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