In vitro selection of unnatural cyclic peptide libraries via mRNA display.
作者： Zhong Ma , Matthew C. T. Hartman
DOI: 10.1007/978-1-61779-379-0_21
关键词:
摘要: The ribosomal synthesis of drug-like peptides containing unnatural amino acids is possible due to the broad substrate specificity ribosome. In this protocol, a reconstituted Escherichia coli translation system (PURE) adapted incorporate into mRNA-displayed peptide libraries, which are used in vitro selection.
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