Mitochondrial genome DNA analysis of the domestic dog: identifying informative SNPs outside of the control region.

摘要: While the mitochondrial control region has proven successful for human forensic evaluations by indicating ethnic origin, domestic dogs (Canis lupus familiaris) of seemingly unrelated breeds often form large groups based on identical sequences. In an attempt to break up these haplotype groups, we have analyzed remaining c. 15,484 base pairs canine genome 79 and used phylogenetic population genetic methods search additional variability in single nucleotide polymorphisms (SNPs). We identified 356 SNPs 65 haplotypes remainder excluding region. The exclusion capacity was found be 0.018. also evaluated same dogs. signals from different fragments do not conflict, but instead support one another provide a larger fragment DNA that can as evidence.