VEGF-receptor signal transduction
作者： Michael J. Cross , Johan Dixelius , Taro Matsumoto , Lena Claesson-Welsh
DOI: 10.1016/S0968-0004(03)00193-2
关键词:
摘要: The vascular endothelial growth factor (VEGF) family of ligands and receptors has been the focus attention in biology for more than a decade. There is now consensus that VEGFs are crucial development neovascularization physiological pathological processes both embryo adult. This facilitated rapid transition to their use clinical applications, example, administration VEGF enhance vascularization ischaemic tissues and, conversely, inhibitors VEGF-receptor function anti-angiogenic therapy. More recent data indicate essential roles haematopoietic cell lymphangiogenesis.
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