Bacterial Lectins as Adhesins

摘要: In 1977, Ofek et al. suggested that proteins with lectin-like properties on bacterial surfaces could serve as adhesins bind the organisms to animal cells. It was found E. coli, bearing type 1 fimbriae specific for mannose, agglutinate red The of many pathogenic bacteria are now thought be carbohydrate-binding proteins, possibly lectins (Table 5–1). Although some members genera Staphylococcus and Streptococcus appear express lack lectin activity, other same known possess surface adhesin functions. Lectins may associated cell wall, outer membrane, or fimbrial structures. More detailed information molecular biology these is provided in Chapter 9. this chapter presented concerning occurrence specificities their role infection. Many have not yet been defined adhesins. A comprehensive review book edited by Mirelman (1986).