Analysis of catecholamines by capillary electrophoresis and capillary electrophoresis–nanospray mass spectrometry: Use of aqueous and non-aqueous solutions compared with physical parameters

作者: Katariina Vuorensola , Heli Sirén , Risto Kostiainen , Tapio Kotiaho

DOI: 10.1016/S0021-9673(02)01256-6

关键词:

摘要: Catecholamines were analysed in aqueous and alcoholic non-aqueous solutions by capillary electrophoresis electrophoresis-mass spectrometry using sheathless nanospray coupling. Decreases the electrophoretic mobilities of catecholamines electroosmotic observed from water to 1-propanol. Separations more efficient all media than water. The diffusion coefficients different determined. solvent had little effect on sensitivity UV or MS detection. Both methods successfully applied analysis urine samples.

参考文章(38)
S. Cherkaoui, L. Geiser, J. -L. Veuthey, Rapid separation of basic drugs by nonaqueous capillary electrophoresis Chromatographia. ,vol. 52, pp. 403- 407 ,(2000) , 10.1007/BF02535710
Helena Keski-Hynnilä, Knut Raanaa, Jyrki Taskinen, Risto Kostiainen, Direct analysis of nitrocatechol-type glucuronides in urine by capillary electrophoresis–electrospray ionisation mass spectrometry and tandem mass spectrometry Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 749, pp. 253- 263 ,(2000) , 10.1016/S0378-4347(00)00413-8
M. Jansson, J. Roeraade, N-methylformamide as a separation medium in capillary electrophoresis Chromatographia. ,vol. 40, pp. 163- 169 ,(1995) , 10.1007/BF02272166
Yvonne Walbroehl, James W. Jorgenson, Capillary zone electrophoresis for the determination of electrophoretic mobilities and diffusion coefficients of proteins Journal of Microcolumn Separations. ,vol. 1, pp. 41- 45 ,(1989) , 10.1002/MCS.1220010110
Katri Huikko, Risto Kostiainen, Analysis of bisphosphonates by capillary electrophoresis-electrospray ionization mass spectrometry. Journal of Chromatography A. ,vol. 872, pp. 289- 298 ,(2000) , 10.1016/S0021-9673(99)01291-1
Jon H. Wahl, David R. Goodlett, Harold R. Udseth, Richard D. Smith, Use of small-diameter capillaries for increasing peptide and protein detection sensitivity in capillary electrophoresis-mass spectrometry Electrophoresis. ,vol. 14, pp. 448- 457 ,(1993) , 10.1002/ELPS.1150140170
Marja-Liisa Riekkola, Matti Jussila, Simo P Porras, István E Valkó, Non-aqueous capillary electrophoresis. Journal of Chromatography A. ,vol. 892, pp. 155- 170 ,(2000) , 10.1016/S0021-9673(00)00108-4
Katariina Vuorensola, Juha Kokkonen, Heli Sirén, Raimo A. Ketola, Optimization of capillary electrophoretic-electrospray ionization-mass spectrometric analysis of catecholamines. Electrophoresis. ,vol. 22, pp. 4347- 4354 ,(2001) , 10.1002/1522-2683(200112)22:20<4347::AID-ELPS4347>3.0.CO;2-J
J. R. Veraart, M. C. Reinders, H. Lingeman, U. A. Th. Brinkman, Non-aqueous capillary electrophoresis of biological samples after at-line solid-phase extraction Chromatographia. ,vol. 52, pp. 408- 412 ,(2000) , 10.1007/BF02535711