Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process

作者: Emily M. LeProust , Bill J. Peck , Konstantin Spirin , Heather Brummel McCuen , Bridget Moore

DOI: 10.1093/NAR/GKQ163

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摘要: We have achieved the ability to synthesize thousands of unique, long oligonucleotides (150mers) in fmol amounts using parallel synthesis of DNA on microarrays. The sequence …

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