INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53

作者: C. A. Schmitt , M. E. McCurrach , E. de Stanchina , R. R. Wallace-Brodeur , S. W. Lowe

DOI: 10.1101/GAD.13.20.2670

关键词:

摘要: The INK4a/ARF locus encodes upstream regulators of the retinoblastoma and p53 tumor suppressor gene products. To compare the impact of these loci on tumor development and …

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