The landscape of the mesenchymal signature in brain tumours

Tarik Tihan, Mitchell S. Berger, Susan M. Chang, Michael D. Prados, Joseph Wiemels, John K. Wiencke, Margaret R. Wrensch, Robert B. Jenkins, Jeanette E. Eckel-Passow, Daniel H. Lachance, Annette M. Molinaro, Kyle M. Walsh, Paul A. Decker, Hugues Sicotte, Melike Pekmezci, Terri Rice, Matt L. Kosel, Ivan V. Smirnov, Gobinda Sarkar, Alissa A. Caron, Thomas M. Kollmeyer, Corinne E. Praska, Anisha R. Chada, Chandralekha Halder, Helen M. Hansen, Lucie S. McCoy, Paige M. Bracci, Roxanne Marshall, Shichun Zheng, Gerald F. Reis, Alexander R. Pico, Brian P. O’Neill, Jan C. Buckner, Caterina Giannini, Jason T. Huse, Arie Perry, Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors The New England Journal of Medicine. ,vol. 372, pp. 2499- 2508 ,(2015) , 10.1056/NEJMOA1407279

Carlo Cusulin, Charles Chesnelong, Pinaki Bose, Misha Bilenky, Karen Kopciuk, Jennifer A. Chan, J. Gregory Cairncross, Steven J. Jones, Marco A. Marra, H. Artee Luchman, Samuel Weiss, Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes. Stem cell reports. ,vol. 5, pp. 1- 9 ,(2015) , 10.1016/J.STEMCR.2015.05.010

Jinan Behnan, Pauline Isakson, Mrinal Joel, Corrado Cilio, Iver A. Langmoen, Einar O. Vik-Mo, Wiaam Badn, Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression. Stem Cells. ,vol. 32, pp. 1110- 1123 ,(2014) , 10.1002/STEM.1614

Cancer Genome Atlas Research Network, None, Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. The New England Journal of Medicine. ,vol. 372, pp. 2481- 2498 ,(2015) , 10.1056/NEJMOA1402121

Kiran Kumar Velpula, Venkata Ramesh Dasari, Andrew J. Tsung, Dzung H. Dinh, Jasti S. Rao, Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1 Oncotarget. ,vol. 2, pp. 1028- 1042 ,(2011) , 10.18632/ONCOTARGET.367

Justin D. Lathia, Stephen C. Mack, Erin E. Mulkearns-Hubert, Claudia L.L. Valentim, Jeremy N. Rich, Cancer stem cells in glioblastoma Genes & Development. ,vol. 29, pp. 1203- 1217 ,(2015) , 10.1101/GAD.261982.115

Andrew W. Bollen, Barry S. Taylor, Annette M. Molinaro, Adam B. Olshen, Susan M. Chang, Jun S. Song, Joseph F. Costello, Tali Mazor, Aleksandr Pankov, Brett E. Johnson, Chibo Hong, Emily G. Hamilton, Robert J.A. Bell, Ivan V. Smirnov, Gerald F. Reis, Joanna J. Phillips, Michael J. Barnes, Ahmed Idbaih, Agusti Alentorn, Jenneke J. Kloezeman, Martine L.M. Lamfers, DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors Cancer Cell. ,vol. 28, pp. 307- 317 ,(2015) , 10.1016/J.CCELL.2015.07.012

Jasmine Lau, Shirin Ilkhanizadeh, Susan Wang, Yekaterina A. Miroshnikova, Nicolas A. Salvatierra, Robyn A. Wong, Christin Schmidt, Valerie M. Weaver, William A. Weiss, Anders I. Persson, STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma Cancer Research. ,vol. 75, pp. 4302- 4311 ,(2015) , 10.1158/0008-5472.CAN-14-3331

Yi-fang Ping, Lu Chen, Hua-liang Xiao, Bin Wang, Liang Yi, Qing-liang Wang, Xue-feng Jiang, Lang Yang, Peng Zhang, Cheng Qian, You-hong Cui, Xia Zhang, Xiu-wu Bian, Xian-zong Ye, Sen-lin Xu, Yan-hong Xin, Shi-cang Yu, Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF-β1 Signaling Pathway Journal of Immunology. ,vol. 189, pp. 444- 453 ,(2012) , 10.4049/JIMMUNOL.1103248

P. Nowell, The clonal evolution of tumor cell populations Science. ,vol. 194, pp. 23- 28 ,(1976) , 10.1126/SCIENCE.959840