Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

作者: Christian Thiede , Sina Koch , Eva Creutzig , Christine Steudel , Thomas Illmer

DOI: 10.1182/BLOOD-2005-08-3167

关键词:

摘要: … In conclusion, NPM1 mutations represent a common genetic … single genetic abnormalities like trisomies (eg, +8 = 11; 19%; +… Comparison of OS (A) and DFS (B) in all patients according …

参考文章(50)
Pierre Fenaux, Claude Chastang, Sylvie Chevret, Miguel Sanz, Hervé Dombret, Eric Archimbaud, Martin Fey, Consuelo Rayon, Françoise Huguet, Jean-Jacques Sotto, Claude Gardin, Pascale Cony Makhoul, Philippe Travade, Eric Solary, Nathalie Fegueux, Dominique Bordessoule, Jesus San Miguel, Harmut Link, Bernard Desablens, Aspasia Stamatoullas, E. Deconinck, Fréderic Maloisel, Sylvie Castaigne, Claude Preudhomme, Laurent Degos, A Randomized Comparison of All Transretinoic Acid (ATRA) Followed by Chemotherapy and ATRA Plus Chemotherapy and the Role of Maintenance Therapy in Newly Diagnosed Acute Promyelocytic Leukemia Blood. ,vol. 94, pp. 1192- 1200 ,(1999) , 10.1182/BLOOD.V94.4.1192
David Bertwistle, Masataka Sugimoto, Charles J. Sherr, Physical and Functional Interactions of the Arf Tumor Suppressor Protein with Nucleophosmin/B23. Molecular and Cellular Biology. ,vol. 24, pp. 985- 996 ,(2004) , 10.1128/MCB.24.3.985-996.2004
Yuki NISHIMURA, Takeshi OHKUBO, Yukio FURUICHI, Hayato UMEKAWA, Tryptophans 286 and 288 in the C-terminal Region of Protein B23.1 are Important for Its Nucleolar Localization Bioscience, Biotechnology, and Biochemistry. ,vol. 66, pp. 2239- 2242 ,(2002) , 10.1271/BBB.66.2239
Derek L. Stirewalt, Jerald P. Radich, The role of FLT3 in haematopoietic malignancies Nature Reviews Cancer. ,vol. 3, pp. 650- 665 ,(2003) , 10.1038/NRC1169
Konstanze Döhner, Richard F. Schlenk, Marianne Habdank, Claudia Scholl, Frank G. Rücker, Andrea Corbacioglu, Lars Bullinger, Stefan Fröhling, Hartmut Döhner, , Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood. ,vol. 106, pp. 3740- 3746 ,(2005) , 10.1182/BLOOD-2005-05-2164
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
C Y Hsu, B Y M Yung, Involvement of nucleophosmin/B23 in TPA-induced megakaryocytic differentiation of K562 cells. British Journal of Cancer. ,vol. 89, pp. 1320- 1326 ,(2003) , 10.1038/SJ.BJC.6601100
R.A. Borer, C.F. Lehner, H.M. Eppenberger, E.A. Nigg, Major nucleolar proteins shuttle between nucleus and cytoplasm Cell. ,vol. 56, pp. 379- 390 ,(1989) , 10.1016/0092-8674(89)90241-9
Emanuela Colombo, Jean-Christophe Marine, Davide Danovi, Brunangelo Falini, Pier Giuseppe Pelicci, Nucleophosmin regulates the stability and transcriptional activity of p53. Nature Cell Biology. ,vol. 4, pp. 529- 533 ,(2002) , 10.1038/NCB814
Dony A. Maiguel, Leslie Jones, Devulapalli Chakravarty, Chonglin Yang, France Carrier, Nucleophosmin Sets a Threshold for p53 Response to UV Radiation Molecular and Cellular Biology. ,vol. 24, pp. 3703- 3711 ,(2004) , 10.1128/MCB.24.9.3703-3711.2004