Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

作者: Yurij Ionov , Miguel A. Peinado , Sergei Malkhosyan , Darryl Shibata , Manuel Perucho

DOI: 10.1038/363558A0

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摘要: … With the exception of cases 78 and 83, the bands corresponding to tumour tissue were a few … Case 89 is the only exception, obtained from New York University Medical College. The …

参考文章(21)
M Perucho, E Winter, C Almoguera, K Forrester, J Jordano, S Kahn, F Yamamoto, The c-K-ras gene and human cancer (review). Anticancer Research. ,vol. 7, pp. 639- 652 ,(1987)
Nelson Fausto, A New Phase for The AJP. American Journal of Pathology. ,vol. 141, pp. 1- 1 ,(1992)
T A Kunkel, Frameshift mutagenesis by eucaryotic DNA polymerases in vitro. Journal of Biological Chemistry. ,vol. 261, pp. 13581- 13587 ,(1986) , 10.1016/S0021-9258(18)67059-0
T A Kunkel, A Soni, Mutagenesis by transient misalignment. Journal of Biological Chemistry. ,vol. 263, pp. 14784- 14789 ,(1988) , 10.1016/S0021-9258(18)68106-2
Kary B. Mullis, Fred A. Faloona, Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods in Enzymology. ,vol. 155, pp. 335- 350 ,(1987) , 10.1016/0076-6879(87)55023-6
Henry T. Lynch, Stephen Lanspa, Thomas Smyrk, Bruce Boman, Patrice Watson, Jane Lynch, Hereditary nonpolyposis colorectal cancer (Lynch syndromes I & II). Genetics, pathology, natural history, and cancer control, part I Cancer Genetics and Cytogenetics. ,vol. 53, pp. 143- 160 ,(1991) , 10.1016/0165-4608(91)90093-A
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Narayana Battula, Lawrence A. Loeb, Clark F. Springgate, Errors in DNA Replication as a Basis of Malignant Changes Cancer Research. ,vol. 34, pp. 2311- 2321 ,(1974)
John Welsh, Michael McClelland, Fingerprinting genomes using PCR with arbitrary primers Nucleic Acids Research. ,vol. 18, pp. 7213- 7218 ,(1990) , 10.1093/NAR/18.24.7213
B Vogelstein, E. Fearon, S. Kern, Hamilton, A. Preisinger, Y Nakamura, R White, Allelotype of colorectal carcinomas Science. ,vol. 244, pp. 207- 211 ,(1989) , 10.1126/SCIENCE.2565047