Diagnostic specificity of the African swine fever virus antibody detection enzyme-linked immunosorbent assay in feral and domestic pigs in the United States.

摘要: African swine fever (ASF) is a highly contagious haemorrhagic disease of pigs that has the potential to cause mortality nearing 100% in naive animals. While an outbreak ASF United States' pig population (domestic and feral) never been reported, introduction devastation pork industry food security. During recovery phase outbreak, antibody detection diagnostic assay would be required prove freedom within previously infected zone eventually nationwide. Animals surviving infection considered carriers could identified through persistence viral antibodies. These antibodies demonstrate exposure not vaccination, as there no vaccine available. A well-established commercial enzyme-linked immunosorbent (ELISA) detects against virus (ASFV), but specificity had determined using serum samples from States. This study describes evaluation World Organization for Animal Health (OIE)-recommended Ingezim PPA COMPAC ELISA comprehensive cohort (n = 1791) collected The was 99.4% (95% confidence interval (CI): [98.9, 99.7]). result this fills gap understanding performance