Dissociations in cognitive memory: the syndrome of developmental amnesia.

摘要: The dearth of studies on amnesia in children has led to the assumption that when damage medial temporal lobe system occurs early life, compensatory capacity immature brain rescues memory functions. An alternative view is such so interferes with development learning and it results not selective cognitive impairments but general mental retardation. Data will be presented counter both these arguments. Results obtained from a series 11 amnesic patients history hypoxic ischaemic sustained perinatally or during childhood indicate regardless age at onset hippocampal pathology, there pronounced dissociation between episodic memory, which severely impaired, semantic relatively preserved. A second characterized by markedly impaired recall spared recognition leading distinction recollection–based versus familiarity–based judgements. These findings are discussed terms locus extent neuropathology associated damage, neural basis ‘remembering’ ‘knowing’, hierarchical model memory.