Clinicopathologic correlations in the oligodendroglioma

作者: Peter C. Burger , Charles E. Rawlings , Edwin B. Cox , Roger E. McLendon , S. Schold Clifford Jr

DOI: 10.1002/1097-0142(19870401)59:7<1345::AID-CNCR2820590719>3.0.CO;2-A

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摘要: To determine the prognostic significance of histologic variables in oligodendroglial neoplasms, presence and degree 15 such were correlated with postoperative survival rates 71 patients. By univariate analysis, prognostically significant factors, order decreasing importance, mitoses (log), necrosis, nuclear cytologic atypia, vascular hypertrophy, proliferation. When studied by stepwise regression, necrosis number contained all useful information. each five analysis was tested Cox model adding a variable to containing other four, found be only independently variable. There positive pairwise correlations between except for atypia necrosis. The association older age mitoses. These results suggest that and, lesser extent, mitotic count are features that, appropriate setting, can used identify "anaplastic" oligodendroglioma.

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