A comparative tissue distribution study of oxytetracycline in rainbow trout, Oncorhynchus mykiss (Walbaum), and chinook salmon, Oncorhynchus tshawytscha (Walbaum)
作者： R. Namdari , S. Abedini , F. C. P. Law
DOI: 10.1046/J.1365-2109.1999.00329.X
关键词:
摘要: Oxytetracycline (OTC), a broad-spectrum antibiotic, is used widely to treat bacterial diseases in farmed fish. In the present study, time course of OTC concentrations freshwater rainbow trout, Oncorhynchus mykiss (Walbaum), and seawater chinook salmon, tshawytscha were compared, tissue by tissue, after receiving bolus dose antibiotic (5 mg kg–1 or 50 mg kg–1) intra-arterially (i.a.). The concentration–time profiles trout tissues found be very similar those corresponding salmon. Therefore, neither water salinity nor fish species seemed play an important role disposition elimination these salmonids. separate experiment, implanted surgically with urinary cannula received single (50 mg kg–1) i.a. Urine was collected from daily for 13 days. amount excreted into bile larger than that eliminated urine. These results show similarity pharmacokinetics salmon render support using study drug other same taxon.
sci-hub.se 参考文章(24)
R Salte, Oxytertracycline residues in rainbow trout (Salmo gairdneri) fed a commercial medicated feed. Acta Veterinaria Scandinavica. ,vol. 23, pp. 150- 152 ,(1982)
S Abedini, R Namdari, F.C.P Law, Comparative pharmacokinetics and bioavailability of oxytetracycline in rainbow trout and chinook salmon. Aquaculture. ,vol. 162, pp. 23- 32 ,(1998) , 10.1016/S0044-8486(97)00306-2
Michiel Onne Elema, Kjell Arne Hoff, Henning Gjelstrup Kristensen, Bioavailability of oxytetracycline from medicated feed administered to Atlantic salmon (Salmo salar L.) in seawater Aquaculture. ,vol. 143, pp. 7- 14 ,(1996) , 10.1016/0044-8486(96)01253-7
Steven M. Plakas, Roland M. McPhearson, Anthony M. Guarino, Disposition and bioavailability of 3H-tetracycline in the channel catfish (Ictalurus punctatus). Xenobiotica. ,vol. 18, pp. 83- 93 ,(1988) , 10.3109/00498258809055139
J.-P. Cravedi, G. Choubert, G. Delous, Digestibility of chloramphenicol, oxolinic acid and oxytetracycline in rainbow trout and influence of these antibiotics on lipid digestibility Aquaculture. ,vol. 60, pp. 133- 141 ,(1987) , 10.1016/0044-8486(87)90305-X
Ron G. Aoyama, Keith M. McErlane, Hildegard Erber, David D. Kitts, Helen M. Burt, High-performance liquid chromatographic analysis of oxytetracycline in chinook salmon following administration of medicated feed. Journal of Chromatography A. ,vol. 588, pp. 181- 186 ,(1991) , 10.1016/0021-9673(91)85021-7
G. A. Strasdine, J. R. McBride, Serum antibiotic levels in adult sockeye salmon as a function of route of administration Journal of Fish Biology. ,vol. 15, pp. 135- 140 ,(1979) , 10.1111/J.1095-8649.1979.TB03576.X
D. W. BRUNO, An investigation into oxytetracycline residues in Atlantic salmon, Salmo salar L. Journal of Fish Diseases. ,vol. 12, pp. 77- 86 ,(1989) , 10.1111/J.1365-2761.1989.TB00279.X
W. D. BLACK, H. W. FERGUSON, P. BYRNE, M. J. CLAXTON, Pharmacokinetic and tissue distribution study of oxytetracycline in rainbow trout following bolus intravenous administration. Journal of Veterinary Pharmacology and Therapeutics. ,vol. 14, pp. 351- 358 ,(1991) , 10.1111/J.1365-2885.1991.TB00848.X
Harry Björklund, Göran Bylund, Temperature-related absorption and excretion of oxytetracycline in rainbow trout (Salmo gairdneri R.) Aquaculture. ,vol. 84, pp. 363- 372 ,(1990) , 10.1016/0044-8486(90)90101-R