Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

作者: Christine M. Ribic , Daniel J. Sargent , Malcolm J. Moore , Stephen N. Thibodeau , Amy J. French

DOI: 10.1056/NEJMOA022289

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摘要: Background Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated …

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