Role of Nutrients in the Cause and Prevention of Oxygen Radical Pathology

摘要: Nutrients function in both the generation and catabolism of oxygen radicals, i.e., as oxidants antioxidants. Experimental animals fed large excesses prooxidant nutrients, such polyunsaturated fatty acids iron, develop pathologies that have been firmly linked to formation toxic concentrations radicals tissues. Similar demonstrated occur a result experimental deficiencies some antioxidant notably vitamin E selenium. Clinical diseases resulting from dietary these nutrients also well documented farm animals. There is evidence pharmacological intakes antioxidants may reduce risk developing clinical associated with radical pathology human subjects consuming normal diet ameliorate tissue damage others. It remains unclear, however, whether occurs humans inadequate or excessive general food supply.