Modifying the mammalian genome by gene targeting
作者： A BRADLEY
DOI: 10.1016/S0958-1669(05)80114-4
关键词:
摘要: Over the past year, gene targeting in mammalian cells has become a facile technology. By using variety of selection and screening protocols, it possible to direct modifications at nucleotide level specific genes, target marker genes so that they expressed under control endogenous promoters delete large regions genome.
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