Systematic review and meta-analysis: Prevalence of incidentally detected pancreatic cystic lesions in asymptomatic individuals.

摘要: Abstract Background & aims Pancreatic cystic lesions (PCLs) are frequent incidental findings. As most PCLs require costly diagnostic evaluation and active surveillance, it is important to clarify their prevalence in asymptomatic individuals. We therefore aimed at performing a systematic review meta-analysis determine it. Methods: search was conducted studies meeting inclusion criteria were included. The of pooled across studies. A random effect model used with assessment heterogeneity. Results 17 studies, 48,860 patients, Only 3 prospective; 5 the US, 7 Europe, 4 Asia 1 Brazil. 8% (95% CI 4–14) considerable heterogeneity (I2 = 99.5%). This higher quality, examining older subjects, smaller cohorts, employing MRCP (24.8% vs 2.7% CT-scan). rate four times US than (12.6% 3.1%). reported mucinous lesions, 4.3% 2–10; I2 = 99.2%), but 0.7% only for worrisome features or high risk stigmata. Conclusion incidentally detected 8%. Mucinous common PCLs, although they rarely present potential indication surgery. observed different rates other geographic Areas suggest that protocols might be necessary help balancing costs effectiveness follow-up investigations subjects.