PCA3 messenger RNA species in benign and malignant prostate tissues
作者： Camille Chypre , Yves Fradet , Ursula Busse
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摘要: This invention concerns the discovery of two distinct PCA3 mRNA sequences. One these sequences corresponds to a short molecule whereas other RNA is longer as it comprises an additional sequence between exon 3 and 4a. The associated with prostate cancer long non-malignant state prostate. Based on differential expression levels sequences, protocols for diagnosis disease are provided. also relates therapeutic approaches cancer.
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