Decreased Antibody-Dependent Cellular Cytotoxicity in Various Types of Leukaemia in Man
作者： Marek Jakóbisiak , Anna Janowska-Wieczorek , Hanna Dobaczewska , Michal Kańtoch , Maria Marczak
DOI: 10.1111/J.1600-0609.1981.TB00470.X
关键词:
摘要: Antibody-dependent cellular cytotoxicity (ADCC) by cells from peripheral blood was studied in patients with; chronic lymphocytic leukaemia (CLL), granulocytic (CGL), acute lymphoblastic (ALL), non-lymphoid (ANLL) and compared with that of healthy donors. The ADCC activity all the types on average lower as control values, being especially low both CLL CGL. Further, it has also been shown non-leukaemic ANLL values. latter observation indicates that, at least ANLL, reduced potential is not due to dilution effector poorly- or non-active leukaemic cells.
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