Is the movement of single cells within solid tissue masses induced by trypsinization

作者: L.L. Wiseman , G.J. Gorbsky , T.S. Melester

DOI: 10.1016/0014-4827(76)90281-0

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摘要: Abstract Embryonic chick cells, labeled with tritiated thymidine ([ 3 H]TdR), isolated trypsin and allowed to “recover” or without were seeded onto the surfaces of solid tissue masses in culture. Autoradiographs revealed extensive migration single, cells within tightly packed cell masses. The ability single infiltrate culture does not, therefore, seem depend upon prior proteolytic treatment.

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