Stem Cells, Hypoxia and Hypoxia-Inducible Factors

作者: Suzanne M. Watt , Grigorios Tsaknakis , Sinead P. Forde , Lee Carpenter

DOI: 10.1007/978-1-60327-227-8_18

关键词:

摘要: Oxygen is a critical environmental factor that regulates the fate of stem cells. In this review, our aims are twofold: (i) to consider contribution oxygen tension niches in which cells and their progeny find themselves have role determining fate, (ii) define regulatory networks control response stem/progenitor hypoxia, particularly those affect early embryonic cell specification hematopoietic development function.

参考文章(271)
Harshal H. Nandurkar, Lorraine Robb, David Tarlinton, Louise Barnett, Frank Köntgen, C. Glenn Begley, Adult Mice With Targeted Mutation of the Interleukin-11 Receptor (IL11Ra) Display Normal Hematopoiesis Blood. ,vol. 90, pp. 2148- 2159 ,(1997) , 10.1182/BLOOD.V90.6.2148
Eric Jauniaux, Frédéric Rodesch, Catherine Donner, Philippe Simon, Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstetrics & Gynecology. ,vol. 80, pp. 283- 285 ,(1992)
Timothy W. Austin, Gregg P. Solar, Francis C. Ziegler, Linda Liem, William Matthews, A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood. ,vol. 89, pp. 3624- 3635 ,(1997) , 10.1182/BLOOD.V89.10.3624
David J. Van Den Berg, Arun K. Sharma, Edward Bruno, Ron Hoffman, Role of Members of the Wnt Gene Family in Human Hematopoiesis Blood. ,vol. 92, pp. 3189- 3202 ,(1998) , 10.1182/BLOOD.V92.9.3189
MG Cipolleschi, P Dello Sbarba, M Olivotto, The role of hypoxia in the maintenance of hematopoietic stem cells Blood. ,vol. 82, pp. 2031- 2037 ,(1993) , 10.1182/BLOOD.V82.7.2031.2031
Adrian L. Harris, Hypoxia — a key regulatory factor in tumour growth Nature Reviews Cancer. ,vol. 2, pp. 38- 47 ,(2002) , 10.1038/NRC704
Christine Fehrer, Regina Brunauer, Gerhard Laschober, Hermann Unterluggauer, Stephan Reitinger, Frank Kloss, Christian Gülly, Robert Gaßner, Günter Lepperdinger, Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan Aging Cell. ,vol. 6, pp. 745- 757 ,(2007) , 10.1111/J.1474-9726.2007.00336.X
Tobias Löfstedt, Erik Fredlund, Linda Holmquist-Mengelbier, Alexander Pietras, Marie Ovenberger, Lorenz Poellinger, Sven Påhlman, Hypoxia inducible factor-2alpha in cancer. Cell Cycle. ,vol. 6, pp. 919- 926 ,(2007) , 10.4161/CC.6.8.4133
Nagy A Habib, Myrtle Y Gordon, Nataša Levičar, Long Jiao, Gilbert Thomas-Black, Stem cell repair and regeneration Imperial College Press. ,(2005) , 10.1142/P389