Chronic traumatic encephalopathy.

摘要: Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative syndrome, which caused by single, episodic, or repetitive blunt force impacts to the head and transfer of acceleration-deceleration forces brain. CTE presents clinically as composite syndrome mood disorders behavioral cognitive impairment, with without sensorimotor impairment. Symptoms may begin persistent symptoms acute brain injury (TBI) following documented episode trauma after latent period that range from days weeks months years, up 40 years cessation TBI. Posttraumatic distinct CTE, can be comorbid clinicopathologic induced focal and/or diffuse, gross microscopic destruction tissue trauma. The sufferer appear grossly unremarkable, but shows evidence primary secondary proteinopathies. proteinopathy tauopathy, while proteinopathies include, are not limited to, amyloidopathy TDP proteinopathy. Reported prevalence rates in cohorts exposed TBI ranges 3 80% across age groups.