Hyperthermia-induced intracellular ionic level changes in tumor cells.
作者： P. N. Yi , C. S. Chang , M. Tallen , W. Bayer , S. Ball
DOI: 10.2307/3576032
关键词:
摘要: The intracellular content of potassium (K) ions in P815 cells decreases when the media pH is lowered, and it increases raised. determination ion therefore requires accurate control medium pH. K measured both by flame emission method analog. 86Rb, exhibits a decline are incubated at 43 degrees C fixed chosen between 7.4 6.7. chloride also while sodium does not change significant amount. Under same hyperthermic conditions fraction unit. Simultaneously, cell water volume 20%, as tritiated water. In final analysis, hyperthermia produces an apparent deficit cellular osmolarity. A possible explanation given.
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