Molecular and Cellular Mechanisms of Hyperthermia
作者： C. Streffer
DOI: 10.1007/978-3-642-57858-8_2
关键词:
摘要: The success of tumor therapy is determined by the efficiency with which killing cells achieved under conditions no or only slight damage to normal tissues. Cell in this sense means that clonogenicity stem destroyed agents such as ionizing radiation, cytotoxic chemicals, heat. Hyperthermia, heating 40°-45°C, can act a agent itself sensitizing combination radiation drugs (Streffer 1990). characteristics and mechanisms sensitization heat will be described other chapters volume; therefore focus chapter on action alone. During prolonged for several hours at temperatures about 42°C below after short shock, become more thermoresistant. These phenomena thermotolerance also later chapter.
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