Transient cells of the developing mammalian telencephalon are peptide-immunoreactive neurons

摘要: In the development of mammalian telencephalon, genesis neurons destined for various layers cerebral cortex is preceded by generation a population cells that comes to reside in subplate and marginal zones1 (see ref. 2 nomenclature). cat, these are present large numbers during development, when their location correlated with arrival accumulation ingrowing axonal systems3–6 synapses7–12. However, as brain matures, disappear white matter layer 1 adult emerge1,13,14. Their disappearance occurs concert invasion cortical plate systems elimination synapses from subplate1,4,7,9,12. Here we report have properties typical mature neurons. They ultra-structural appearance receive synaptic contacts. also long projections immunoreactive MAP2 (microtubule associated protein 2). Further, subpopulations one several neuropeptides. These observations suggest fetal early postnatal telencephalon function circuitry disappears adulthood.