作者: Jean‐Christophe Olivier , Ramon Huertas , Hwa Jeong Lee , Frederic Calon , William M. Pardridge
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摘要: Purpose. This work describes the synthesis of pegylated immunonanoparticles by conjugation an anti-transferrin receptor monoclonal antibody (MAb) to maleimide-grafted nanoparticles prepared from poly(lactic acid) (PLA) and a bi-functional polyethyleneglycol (PEG).