miRNAs in pregnancy-related complications
作者： Alexandra Lycoudi , Danai Mavreli , Ariadni Mavrou , Nikolas Papantoniou , Aggeliki Kolialexi
DOI: 10.1586/14737159.2015.1053468
关键词:
摘要: MicroRNAs (miRNAs) constitute a highly conserved class of small non-coding RNAs, involved in post-transcriptional regulation processes by modifying the expression specific mRNAs. During placental development, cell differentiation, adhesion, migration, apoptosis and angiogenesis are regulated miRNAs aberrant has been associated with pathogenesis pregnancy-related complications. Recent studies focusing on maternal peripheral blood miRNA profiling showed different between normal complicated pregnancies, providing valuable information about pathophysiological role identifying potential biomarkers for monitoring pregnancy This review summarizes current knowledge field presents possible use as early detection these
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