BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAFV600E but not KRAS mutations

作者: A Preto , J Figueiredo , S Velho , AS Ribeiro , P Soares

DOI: 10.1002/PATH.2295

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摘要: … After BRAF down-regulation, we found a more pronounced decrease in ERK1/2 … Upon BRAF inhibition, we also found an increase in p27 Kip1 levels and a more pronounced decrease …

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