The role and timing of decompression in acute spinal cord injury: what do we know? What should we do?

作者: Michael G. Fehlings , Lali H.S. Sekhon , Charles Tator

DOI: 10.1097/00007632-200112151-00017

关键词:

摘要: The management of acute spinal cord injury has traditionally concentrated on preventative measures as well as, for the better part previous century, conservative care. Pharmacologic interventions, in particular intravenous methylprednisolone therapy, have shown modest improvements clinical trials and are still undergoing evaluation. More recent interest focused role surgical reduction decompression, particularly "early" surgery. A review current evidence available literature suggests that there is no standard care regarding timing decompression. There insufficient data to support overall treatment standards or guidelines this topic. are, however, Class II indicating early surgery (<24 hours) may be done safely after SCI. Furthermore, III suggest a urgent decompression setting 1) bilateral facet dislocation 2) incomplete with neurologically deteriorating patient. Whereas biologic from experimental studies animals improve neurologic recovery SCI, relevant time frame humans remains unclear. To date, patients SCI only supported by limited accordingly can considered practice option. Accordingly, strong rationale undertake prospective, controlled evaluate

参考文章(111)
Harmody Rm, Miller Cf, Brodkey Js, The syndrome of acute central cervical spinal cord injury revisited. Surgical Neurology. ,vol. 14, pp. 251- 257 ,(1980)
Frederick M. Maynard, Glenn G. Reynolds, Steven Fountain, Conal Wilmot, Richard Hamilton, Neurological prognosis after traumatic quadriplegia. Three-year experience of California Regional Spinal Cord Injury Care System. Journal of Neurosurgery. ,vol. 50, pp. 611- 616 ,(1979) , 10.3171/JNS.1979.50.5.0611
Jerald S. Brodkey, David E. Richards, James P. Blasingame, Frank E. Nulsen, Reversible spinal cord trauma in cats. Additive effects of direct pressure and ischemia. Journal of Neurosurgery. ,vol. 37, pp. 591- 593 ,(1972) , 10.3171/JNS.1972.37.5.0591
Ralph J. Marino, John F. Ditunno, Gerald J. Herbison, Lillian Wu, Recovery of zero-grade muscles in the zone of partial preservation in motor complete quadriplegia. Archives of Physical Medicine and Rehabilitation. ,vol. 73, pp. 40- 43 ,(1992) , 10.5555/URI:PII:000399939290224K
R B Delamarter, J Sherman, J B Carr, Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression Journal of Bone and Joint Surgery, American Volume. ,vol. 77, pp. 1042- 1049 ,(1995) , 10.2106/00004623-199507000-00010
HENRY H. BOHLMAN, JOHN S. KIRKPATRICK, RICK B. DELAMARTER, MARVIN LEVENTHAL, Anterior decompression for late pain and paralysis after fractures of the thoracolumbar spine. Clinical Orthopaedics and Related Research. ,vol. 300, pp. 24- 29 ,(1994) , 10.1097/00003086-199403000-00003
Aizik Wolf, Lion Levi, Stuart Mirvis, John Ragheb, Stephen Huhn, Daniele Rigamonti, Walker L. Robinson, Operative management of bilateral facet dislocation Journal of Neurosurgery. ,vol. 75, pp. 883- 890 ,(1991) , 10.3171/JNS.1991.75.6.0883