Do androgens regulate growth hormone-binding protein in adult man?
作者： TP Ip , DM Hoffman , AJ O'Sullivan , KC Leung , KK Ho
DOI: 10.1210/JCEM.80.4.7714101
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摘要: To determine whether adult serum GH-binding protein (GHBP) is regulated by androgen, GHBP concentrations were compared between 20 normal and 18 hypogonadal men matched for age body mass index, the effect of im testosterone treatment (250 mg enanthate) on levels in was studied. Nine subjects had coexistent GH deficiency. Serum concentration measured a ligand immunofunctional assay. The mean level untreated not significantly different from that (0.98 +/- 0.15 vs. 1.17 0.16 nmol/L). insulin-like growth factor I (IGF-I) lower (132 22 206 17 ng/mL; P < 0.01). Basal (3.7 0.7 nmol/L) increased during to 29.1 2.8 nmol/L, which higher than (22.6 1.9 hypogonada...
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