Twist is inversely associated with claudins in germ cell tumors of the testis
作者： PÄIVI VÄRE , YLERMI SOINI
DOI: 10.1111/J.1600-0463.2010.02638.X
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摘要: Vare P, Soini Y. Twist is inversely associated with claudins in germ cell tumors of the testis. APMIS 2010; 118: 640–7. We investigated expression 1, 3–7 and transcriptional factor twist a set testicular tumors. The material consisted 17 seminomas, 13 teratomas, 9 teratocarcinomas, 20 embryonal carcinomas mixed They were immunostained antibodies to twist. As expected, all variably present epithelial elements or differentiation, but intensity varied depending on claudin type. Mesenchymal teratomatous remained negative for claudins. Expression different was less intense inconsistent other types Choriocarcinomatous expressed relatively strongly 4 weaker positivity 5–7, while 1 3 negative. Seminomas showed only 5 7. most seminoma followed by carcinoma. several (claudins 3, 6). Germ vary their 1–7. claudins, suggesting that it takes part downregulation
sci-hub.se 参考文章(26)
Takashi Kojima, Ken-ichi Takano, Toshinobu Yamamoto, Masaki Murata, Seiichi Son, Masafumi Imamura, Hiroshi Yamaguchi, Makoto Osanai, Hideki Chiba, Tetsuo Himi, Norimasa Sawada, Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes. Liver International. ,vol. 28, pp. 534- 545 ,(2007) , 10.1111/J.1478-3231.2007.01631.X
Hisashi Miyamori, Takahisa Takino, Yuko Kobayashi, Hideaki Tokai, Yoshifumi Itoh, Motoharu Seiki, Hiroshi Sato, Claudin Promotes Activation of Pro-matrix Metalloproteinase-2 Mediated by Membrane-type Matrix Metalloproteinases Journal of Biological Chemistry. ,vol. 276, pp. 28204- 28211 ,(2001) , 10.1074/JBC.M103083200
Michael Zeisberg, Eric G. Neilson, Biomarkers for epithelial-mesenchymal transitions Journal of Clinical Investigation. ,vol. 119, pp. 1429- 1437 ,(2009) , 10.1172/JCI36183
Z F Chen, R R Behringer, twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes & Development. ,vol. 9, pp. 686- 699 ,(1995) , 10.1101/GAD.9.6.686
Gerd Krause, Lars Winkler, Sebastian L. Mueller, Reiner F. Haseloff, Jörg Piontek, Ingolf E. Blasig, Structure and function of claudins. Biochimica et Biophysica Acta. ,vol. 1778, pp. 631- 645 ,(2008) , 10.1016/J.BBAMEM.2007.10.018
H. TAKALA, J. SAARNIO, H. WIIK, Y. SOINI, Claudins 1, 3, 4, 5 and 7 in esophageal cancer: loss of claudin 3 and 4 expression is associated with metastatic behavior. Apmis. ,vol. 115, pp. 838- 847 ,(2007) , 10.1111/J.1600-0463.2007.APM_656.X
Ofelia M. Martínez-Estrada, Albert Cullerés, Francesc X. Soriano, Hector Peinado, Victoria Bolós, Fernando O. Martínez, Manuel Reina, Amparo Cano, Myriam Fabre, Senén Vilaró, The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells. Biochemical Journal. ,vol. 394, pp. 449- 457 ,(2006) , 10.1042/BJ20050591
Norimasa Sawada, Masaki Murata, Keisuke Kikuchi, Makoto Osanai, Hirotoshi Tobioka, Takashi Kojima, Hideki Chiba, Tight junctions and human diseases. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan. ,vol. 36, pp. 147- 156 ,(2003) , 10.1007/S00795-003-0219-Y
Jennifer L. Holmes, Christina M. Van Itallie, Julia E. Rasmussen, James M. Anderson, Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns Gene Expression Patterns. ,vol. 6, pp. 581- 588 ,(2006) , 10.1016/J.MODGEP.2005.12.001
Steven D Billings, Shaun V Walsh, Cyril Fisher, Asma Nusrat, Sharon W Weiss, Andrew L Folpe, Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation. Modern Pathology. ,vol. 17, pp. 141- 149 ,(2004) , 10.1038/MODPATHOL.3800042