Albuminuria and carotid atherosclerosis as predictors of cognitive function in a general population.
作者： Sigbjørn O. Rogne , Marit D. Solbu , Kjell Arne Arntzen , Marit Herder , Ellisiv B. Mathiesen
DOI: 10.1159/000353701
关键词:
摘要: Background/Aims: Albuminuria and carotid atherosclerosis are predictors of cardiovascular disease potential cognitive decline. Our aim was to study whether albuminuria an early predictor function independent in a general population. Methods: The population comprised 1,577 adults without self-reported stroke. In 1994 2007 all were screened for risk factors, urinary albumin-creatinine ratio (ACR), intima-media thickness total plaque area (TPA). Endpoints neuropsychological test results from the digit symbol test, finger-tapping Mini Mental Status Examination 12-word parts 1 2. Multivariate linear regression used assess associations. Results: Higher ACR, ΔACR, thickness, TPA ΔTPA independently predicted lower score on test. ΔACR part (immediate recall). Smoking scores tests atherosclerosis. Conclusions: suggest that albuminuria, smoking executive motor tempo.
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