Expression of Lewis(a), sialyl Lewis(a), Lewis(x) and sialyl Lewis(x) antigens as prognostic factors in patients with colorectal cancer.

作者: Tohru Nakagoe , Kiyoyasu Fukushima , Atsushi Nanashima , Terumitsu Sawai , Takashi Tsuji

DOI: 10.1155/2000/149851

关键词:

摘要: BACKGROUND: Altered expression of blood group-related carbohydrate antigens such as sialyl Lewis (Le)x antigen in tumours is associated with tumour progression behaviour and subsequent prognosis. However, the prognostic value Le-related colorectal remains unclear.

参考文章(40)
L. H. Sobin, Jeremy R. Jass, Basil C. Morson, Histological typing of intestinal tumours ,(1976)
Tatsuro Irimura, Takao Yamori, Sen-itiroh Hakomori, Karen R. Cleary, Yoshifumi Matsushita, David M. Ota, Stuart D. Hoff, Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma. Cancer Research. ,vol. 49, pp. 6883- 6888 ,(1989)
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
Glenn Y. Terashita, Paul I. Terasaki, Jane Galton, Masaki Hirota, Kiyoyasu Fukushima, Masaaki Kawahara, Detection of tumor-associated antigens in the sera of lung cancer patients by three monoclonal antibodies. Cancer Research. ,vol. 45, pp. 6453- 6456 ,(1985)
I Eggens, B Fenderson, T Toyokuni, B Dean, M Stroud, S Hakomori, Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells. Journal of Biological Chemistry. ,vol. 264, pp. 9476- 9484 ,(1989) , 10.1016/S0021-9258(18)60556-3
Reiji Kannagi, Hiroo Imura, Sen-itiroh Hakomori, Kouichi Zenita, Yasuo Fukushi, Katsuyoshi Shigeta, Shigeyuki Itai, Aiko Kitahara, Tetsuya Tachikawa, Atsunari Noda, Sadahito Shin, Hisanobu Hirano, Midori Abe, Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing epitopes consisting of sialyl or sialyl-fucosyl type 1 chain. Cancer Research. ,vol. 48, pp. 3856- 3863 ,(1988)
Sen-itiroh Hakomori, Aberrant glycosylation in cancer cell membranes as focused on glycolipids: overview and perspectives. Cancer Research. ,vol. 45, pp. 2405- 2414 ,(1985)
T. F. Ørntoft, E. Nudelman, S. Hakomori, M. R. Stroud, L. Schibig, S. Nance, A. K. Singhal, H. Clausen, Profiles of Lewisx-containing Glycoproteins and Glycolipids in Sera of Patients with Adenocarcinoma Cancer Research. ,vol. 50, pp. 1375- 1380 ,(1990)
Edward Nudelman, Paul I. Terasaki, Hiroyuki Togashi, Sen-Itiroh Hakomori, Yasuo Fukushi, Masaki Hirota, Kiyoyasu Fukushima, Naofuml Suyama, Akemi Wakisaka, David Chia, Characterization of Sialosylated Lewisx as a New Tumor-associated Antigen Cancer Research. ,vol. 44, pp. 5279- 5285 ,(1984)
Katsunori Tauchi, Kennichi Kakudo, Takao Machimura, Hiroyasu Makuuchi, Toshio Mitomi, Immunohistochemical studies of blood group-related antigens in human superficial esophageal carcinomas. Cancer. ,vol. 67, pp. 3042- 3050 ,(1991) , 10.1002/1097-0142(19910615)67:12<3042::AID-CNCR2820671219>3.0.CO;2-L