Breast Cancer in Young Women in Latin America: An Unmet, Growing Burden

摘要: BACKGROUND Breast cancer (BC) is the leading cause of malignancy-related deaths among women aged ≤ 45 years. There are unexplored and uncertain issues for BC in this particular group Latin America. The aim study to evaluate incidence mortality young related clinicopathological survivorship aspects region. MATERIALS AND METHODS Data were obtained from Globocan 2008 International Agency Research on Cancer's Cancer Incidence Five Continents series plus databases. We requested collaboration 12 different national institutes America through SLACOM, American Caribbean Society Medical Oncology, conducted a systematic literature review obtain local data regarding prevalence their characteristics, outcomes, survivorship-related issues. RESULTS proportions <44 years higher when compared with those developed countries (20% vs. 12% 14% 7%, respectively). found only few addressing topic, varied between 8% 14%. Stage II III disease, high histological grade, triple-negative HER2 features frequently observed patients. CONCLUSION rising call action It necessary monitor epidemiological clinical reliable registries consider implementation protocols education patients health professionals. This unmet, growing burden must be considered as top priority programs fight against BC, models specialized units should implemented provide better care emergent challenge.