Fc variants with enhanced binding to fcrn and prolonged half-life

作者: Huawei Qiu , Brian Mackness

DOI:

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摘要: The present disclosure provides binding polypeptides (e.g., antibodies and immunoadhesins) comprising a modified Fc domain. also nucleic acids encoding the polypeptides, recombinant expression vectors, host cells for making such polypeptides. Methods of using disclosed herein to treat disease are provided.

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