The Effect of Omega-3 Fatty Acids on Biomarkers of Inflammation: A Rapid Evidence Assessment of the Literature
作者： Raheleh Khorsan , Cindy Crawford , John A. Ives , Avi R. Walter , Wayne B. Jonas
DOI: 10.7205/MILMED-D-14-00339
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摘要: ABSTRACT Introduction: Previous studies of omega-3 fatty acids report improved outcomes where inflammation is a key factor. The objective this systematic review to evaluate effects omega-3s on inflammatory biomarkers. Methods: Randomized clinical that measured the influence biomarkers were identified using comprehensive search. Eligible rated with American Dietetic Association Evidence Analysis Manual and Grading Recommendations, Assessment, Development Evaluation (GRADE) process examine study quality risk/benefit. Results: 112 included. Over 65% reported statistically significant effects. majority scored as low risk bias (high quality) strong (cardiac populations critically ill) weak (Alzheimer's Disease, hypertriglyceridemia/diabetes, obesity) risk/benefit ratio evidence for modulation There was inadequate data determine GRADE for...
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sci-hub.se 参考文章(163)
Artemis P. Simopoulos, Omega-3 Fatty Acids in Inflammation and Autoimmune Diseases Journal of The American College of Nutrition. ,vol. 21, pp. 495- 505 ,(2002) , 10.1080/07315724.2002.10719248
Z. M. Jiang, D. W. Wilmore, X. R. Wang, J. M. Wei, Z. T. Zhang, Z. Y. Gu, S. Wang, S. M. Han, H. Jiang, K. Yu, Randomized clinical trial of intravenous soybean oil alone versus soybean oil plus fish oil emulsion after gastrointestinal cancer surgery British Journal of Surgery. ,vol. 97, pp. 804- 809 ,(2010) , 10.1002/BJS.6999
Trine Madsen, Jeppe H. Christensen, Mogens Blom, Erik B. Schmidt, The effect of dietary n-3 fatty acids on serum concentrations of C-reactive protein: a dose-response study. British Journal of Nutrition. ,vol. 89, pp. 517- 522 ,(2003) , 10.1079/BJN2002815
Thomas M. Stulnig, Bianca K. Itariu, Maximilian Zeyda, Lukas Leitner, Rodrig Marculescu, Treatment with n-3 Polyunsaturated Fatty Acids Overcomes the Inverse Association of Vitamin D Deficiency with Inflammation in Severely Obese Patients: A Randomized Controlled Trial PLoS ONE. ,vol. 8, pp. e54634- ,(2013) , 10.1371/JOURNAL.PONE.0054634
Matthias W. Wichmann, Paul Thul, Hans-Dieter Czarnetzki, Bart J. Morlion, Matthias Kemen, Karl-Walter Jauch, Evaluation of clinical safety and beneficial effects of a fish oil containing lipid emulsion (Lipoplus, MLF541): data from a prospective, randomized, multicenter trial. Critical Care Medicine. ,vol. 35, pp. 700- 706 ,(2007) , 10.1097/01.CCM.0000257465.60287.AC
Eduard Cabré, Míriam Mañosa, Miquel A. Gassull, Omega-3 fatty acids and inflammatory bowel diseases - a systematic review. British Journal of Nutrition. ,vol. 107, ,(2012) , 10.1017/S0007114512001626
Michelle A. Micallef, Manohar L. Garg, Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals Atherosclerosis. ,vol. 204, pp. 476- 482 ,(2009) , 10.1016/J.ATHEROSCLEROSIS.2008.09.020
M. Jit, TNF-α neutralization in cytokine-driven diseases: a mathematical model to account for therapeutic success in rheumatoid arthritis but therapeutic failure in systemic inflammatory response syndrome Rheumatology. ,vol. 44, pp. 323- 331 ,(2005) , 10.1093/RHEUMATOLOGY/KEH491
Joel M. Kremer, David A. Lawrence, William Jubiz, Ralph Digiacomo, Richard Rynes, Lee E. Bartholomew, Malcolm Sherman, Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. Arthritis & Rheumatism. ,vol. 33, pp. 810- 820 ,(1990) , 10.1002/ART.1780330607
Patrick A Morrissey, Mairead Kiely, Neil J Mann, Karen J Murphy, Andrew J Sinclair, Karen Galvin, Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo. Asia Pacific Journal of Clinical Nutrition. ,vol. 15, pp. 418- 424 ,(2006)