Tissue distribution and elimination of florfenicol in tilapia (Oreochromis niloticus×O. caureus) after a single oral administration in freshwater and seawater at 28 °C
作者： Jing-Bin Feng , Xiao-Ping Jia , Liu-Dong Li
DOI: 10.1016/J.AQUACULTURE.2008.01.002
关键词:
摘要: Tissue distribution and elimination of florfenicol in seawater-acclimated tilapia were compared with those freshwater at 28 degrees C after they given a single oral dose 10 mg/kg body weight (b.w.). In most sampling time points, the concentrations tissues (muscle, liver, kidney, gill bile) higher than seawater tilapia. major phase half-lives (T-1/2 beta) all (except for longer These findings indicated that level was more rapid The main excretion pathway (gill excretion) drug different from (bile tilapia, which should be responsible considerable difference pharmacokinetics (c) 2008 Elsevier B.V. All rights reserved.
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