Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

作者: Sandra Misale , Rona Yaeger , Sebastijan Hobor , Elisa Scala , Manickam Janakiraman

DOI: 10.1038/NATURE11156

关键词:

摘要: … KRAS mutations as frequent drivers of acquired resistance to cetuximab in colorectal cancers, indicate that the emergence of KRAS … drug resistance resulting from alterations in KRAS …

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