Pyropheophorbides conjugates and their use in photodynamic therapy

摘要: Conjugate are formed by covalently linking a target-specific compound to pyropheophorbide which conjugated injected into host and accumulate in tumor tissue higher degree than surrounding normal tissues. When the component of conjugate is exposed particular wavelength light becomes cytotoxic destroying or diseased without causing irreversible damage. The compounds have been shown variety characteristics when used photodynamic therapy. These further improved bound target specific such as ligand capable binding cellular receptor (e.g. growth hormones factors) an antibody antigen.