Nature of the Tumor-localizing Components of Hematoporphyrin Derivative
作者： George Morstyn , Andrew H. Kaye , Ralph M. Böhmer , Panayiotis A. Scourides
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摘要: Hematoporphyrin derivative linked by ether bonds (HE) was synthesized unambiguous procedures in order to compare its properties hematoporphyrin (HpD). Reverse phase high performance liquid and gel filtration chromatography were used the HE derivatives HpD. The cellular uptake of compared HpD using WEHI 3B (D+) cell line shown be taken up a degree manner similar efficiency porphyrins as photosensitizers V79 line. more efficient sensitizing cells than vivo tumor localizing CBA mice bearing C6 cerebral glioma, BALB/c EMT6 mammary tumor. localized both models effectively We conclude that are very
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