Hypoxia- and Vascular Endothelial Growth Factor-Induced Stromal Cell-Derived Factor-1α/CXCR4 Expression in Glioblastomas: One Plausible Explanation of Scherer's Structures

作者: David Zagzag , Mine Esencay , Olga Mendez , Herman Yee , Iva Smirnova

DOI: 10.2353/AJPATH.2008.071197

关键词:

摘要: … ERK1/2 in glioma cells, all critical signaling molecules in glioma … Based on our in vivo observations in human GBMs, we … the migration of CXCR4-expressing glioma tumor cells toward …

参考文章(58)
H. J. Scherer, Structural Development in Gliomas American Journal of Cancer. ,vol. 34, pp. 333- 351 ,(1938) , 10.1158/AJC.1938.333
David G. Wilkinson, M.Angela Nieto, Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods in Enzymology. ,vol. 225, pp. 361- 373 ,(1993) , 10.1016/0076-6879(93)25025-W
David N. Louis, WHO classification of tumours of the central nervous system International Agency for Research on Cancer. ,(2007)
Shugang Ge, Steve Dudas, Jorge A. Gutiérrez, Sandra A. Rempel, Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma Clinical Cancer Research. ,vol. 6, pp. 102- 111 ,(2000)
Kenneth J. Pienta, Norton S. Taichman, Russell S. Taichman, Laurie K. McCauley, Evan T. Keller, Carlton Cooper, Use of the Stromal Cell-derived Factor-1/CXCR4 Pathway in Prostate Cancer Metastasis to Bone Cancer Research. ,vol. 62, pp. 1832- 1837 ,(2002)
Y-C Yang, Z-Y Lee, C-C Wu, T-C Chen, C-L Chang, C-P Chen, None, CXCR4 expression is associated with pelvic lymph node metastasis in cervical adenocarcinoma. International Journal of Gynecological Cancer. ,vol. 17, pp. 676- 686 ,(2007) , 10.1111/J.1525-1438.2007.00841.X
Carmen Eckerich, Svenja Zapf, Regina Fillbrandt, Sonja Loges, Manfred Westphal, Katrin Lamszus, Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration International Journal of Cancer. ,vol. 121, pp. 276- 283 ,(2007) , 10.1002/IJC.22679
Nirmala Chandrasekar, Sanjeeva Mohanam, Meena Gujrati, William C Olivero, Dzung H Dinh, Jasti S Rao, Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells Oncogene. ,vol. 22, pp. 392- 400 ,(2003) , 10.1038/SJ.ONC.1206164
M Ehtesham, J A Winston, P Kabos, R C Thompson, CXCR4 expression mediates glioma cell invasiveness. Oncogene. ,vol. 25, pp. 2801- 2806 ,(2006) , 10.1038/SJ.ONC.1209302
Peter Kabos, Yasuharu Akasaki, Keith L. Black, Xiangpeng Yuan, Gentao Liu, Nancy H.C. Chung, John S. Yu, Moneeb Ehtesham, Glioma Tropic Neural Stem Cells Consist of Astrocytic Precursors and Their Migratory Capacity Is Mediated by CXCR4 Neoplasia. ,vol. 6, pp. 287- 293 ,(2004) , 10.1593/NEO.3427