Guillain-Barré syndrome without sensory loss (acute motor neuropathy)A subgroup with specific clinical, electrodiagnostic and laboratory features

摘要: We analysed data obtained from 27 out of a group 147 patients with Guillain-Barre syndrome, who did not have sensory loss during follow-up period 6 months (motor syndrome). These had distinctive clinical pattern compared the other 120 syndrome patients. The course was marked by more rapid onset weakness (3.9 versus 6.1 days, P = 0.002), an earlier nadir (6.3 9.1 < 0.001), initially predominant distal (67% 27%, sparing cranial nerves (26% 68%, 0.001) and disease often preceded gastro-intestinal illness (41% 13%, caused Campylobacter jejuni infection 28% in patients, 0.001). High titres anti-GM1 antibodies were also significantly common motor (42% 5%, Electromyographic at revealed little or no evidence for demyelination. Abundant denervation activity present half response to immune globulin treatment good but plasma exchange fewer reached stage independent locomotion after especially if acute neuropathy occurred C.jejuni infection.(ABSTRACT TRUNCATED AT 250 WORDS)