Preparation and evaluation of a hydroxycyclohexyl derivative of sephadex LH-20

作者: R.A. Anderson , B.A. Knights , C.J.W. Brooks

DOI: 10.1016/S0021-9673(01)91839-4

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摘要: Abstract Sephadex LH-20 has been substituted with hydroxycyclohexyl residues to give a stable gel for use in lipophilic chromatography. The can be used straight-phase and reversed-phase systems. Separations of model set steroidal compounds are described. Hydroxysteroids epimeric at C-3, C-7, C-11, C-17 or C-20 have separated as the free alcohols system. Five ▶ 5 -steroids from corresponding dihydrosteroids 5α-series.

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