Impact of intraoperative magnetic resonance imaging and functional neuronavigation on surgical outcome in patients with gliomas involving language areas.

摘要: Balancing the benefit of extensive tumor resection with consequence potential postoperative language deficits remains a challenge in glioma surgery involving areas. This study is designed to evaluate impact intraoperative magnetic resonance imaging (iMRI) and functional neuronavigation on surgical outcome patients gliomas Two hundred seventeen were prospectively enrolled, 124 group underwent iMRI neuronavigation-guided microsurgery 93 control conventional navigation-guided microsurgery. Extent volume (EoR) rate gross total (rGTR) calculated perioperatively. Aphasia quotient (AQ) was assessed change function perioperatively at 6-month follow-up. Survival for glioblastoma, including progression-free survival (PFS) overall (OS), recorded. In 198 (112 86 group), EoR (95.50 versus 89.85 %, p < 0.001) rGTR (69.60 47.70 = 0.002) significantly higher group, functions also better follow-up (87.47 78.73, 0.001). Furthermore, new aphasia occurred 34.8 % whereas it only 2.3 (p addition, PFS (12.5 6.6 m, 0.003) OS (19.6 13.0 glioblastomas dramatically prolonged than group. These results indicated that may help maximize resection, minimize areas, improve time glioblastomas.